关键护理药疗文学的主要出版物:2022年
Payal K Gurnani1, Brooke Barlow1, Bryan Boling2
1Department of Pharmacy, Memorial Hermann The Woodlands Medical Center, The Woodlands, TX.
Critical care explorations
|September 27, 2023
概括
本综述强调了2022年关键的临床药物治疗研究重症患者. 它确定了在镇静,败血症和抗生素使用等领域的有影响力的研究,影响了临床实践.
科学领域:
- 关键护理医学 关键护理医学
- 药物治疗 药物治疗
- 临床药房 临床药房
背景情况:
- 2022年发表了大量关于重症监护药物治疗的试验.
- 有效的药物治疗管理对于重症患者至关重要.
研究的目的:
- 总结从2022年起最具影响力的药物治疗出版物.
- 提供关于关键病患者护理进展的见解.
主要方法:
- 系统搜索PubMed和临床药房和药理学药理学文献更新.
- 包括在2022年发表的随机对照试验,前性研究和系统性审查/元分析.
- 将文章分为临床领域的分层,并使用修改后的Delphi过程选择有影响力的出版物.
主要成果:
- 44篇文章被选择并分为六个临床领域分层.
- 关键话题包括用德克斯梅托米丁镇静,β-阻断剂,在败血症休克时的液体限制,VTE预防,肺炎时的抗生素持续时间,以及社区获得的肺炎时的甲基普雷迪尼索隆.
- 选出的文章包括三项随机对照试验和三项系统性审查/元分析.
结论:
- 本综述提供了对2022年对重症患者的药物治疗研究有影响力的视角.
- 总结的研究结果有可能影响重症监护机构当前的临床实践.
相关概念视频
Cardiopulmonary Resuscitation IV: Pharmacological Management
13
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
13
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
454
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
454
Heart Failure Drugs: Inotropic Agents
611
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
611
Heart Failure Drugs: β-Blockers
357
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
357
Coronary Artery Disease V: Interprofessional Care
9
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
9
Cardiomyopathy V: Interprofessional Care
14
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
14


