在中年从未吸烟者中,间歇性肺异常的高患病率
Ida Pesonen1,2, Fredrik Johansson3, Åse Johnsson4,5
1Respiratory Medicine Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
ERJ open research
|September 27, 2023
概括
间歇性肺异常 (ILA) 在中年瑞典人中很常见,即使在从未吸烟的人中也是如此. 这些发现表明,在从未吸烟的人群中,ILA的诊断可能不足,他们通常不会接受查.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 间歇性肺部异常 (ILA) 是胸部CT扫描中的偶然发现.
- 这些模式可以表明早期的纤维化肺病.
研究的目的:
- 为了估计瑞典人口中ILA的患病率.
- 专门研究从未吸烟者中的ILA患病率.
- 探索ILA与人口统计,并发症和症状之间的关联.
主要方法:
- 利用了瑞典心肺生物图像研究 (SCAPIS) 的数据.
- 包括29521名年龄在50-64岁之间的参与者,他们接受了CT扫描,螺旋计和问卷.
- 根据特定的CT发现定义的ILA,如囊,地面玻璃不透明度和蜂.
主要成果:
- 整体ILA患病率为9.7% (0.5%纤维化).
- 在从未吸烟者中,ILA患病率为7.9% (0.3%纤维化).
- ILA与年龄,吸烟史,慢性支气管炎,癌症,冠状动脉分数,CRP,限制性螺旋计模式和扩散能力受损有关,但没有报告症状.
结论:
- ILA在瑞典中年人群中普遍存在,包括从未吸烟的人.
- 由于缺乏有针对性的查,患有ILA的从未吸烟者可能面临低诊断的风险.
相关概念视频
01:20COPD: Pathogenesis and Clinical Features
327
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
327
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.8K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
01:25Pulmonary Function Tests
359
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
359
01:17Other Pulmonary Disorders
865
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
865