耐火和无法解释的慢性咳对患者生活的负担:一个队列研究
Luis Puente-Maestu1, Ignacio Dávila2, Santiago Quirce3
1Servicio de Neumología, Hospital Universitario Gregorio Marañón, UCM, Madrid, Spain.
ERJ open research
|September 27, 2023
概括
慢性咳显著影响生活质量和日常活动. 患者,尤其是女性,由于不耐药或不明原因的慢性咳,体验到幸福感降低和身体/心理健康负担.
科学领域:
- 肺部病理学 肺部病理学
- 生活质量研究 研究 生命质量研究
- 患者报告的结果
背景情况:
- 慢性咳,定义为持续8周或更长时间,大大降低了患者的生活质量 (QoL).
- 耐火性慢性咳 (RCC) 和无法解释的慢性咳 (UCC) 是具有重大患者负担的具有挑战性的临床场景.
研究的目的:
- 评估慢性咳对RCC或UCC患者的QoL和日常功能所感知的影响.
- 通过患者报告的结果,探索慢性咳对身体和心理的影响.
主要方法:
- 进行了一项多中心的非干预性调查研究.
- 咳的严重程度使用视觉模拟量表 (VAS) 进行测量.
- 使用莱斯特咳问卷 (LCQ) 评估生活质量,并对日常生活影响提出具体问题.
主要成果:
- 有191名RCC/UCC患者参与了这项研究,121名RCC患者,149名女性.
- 平均咳严重程度VAS得分为62.9毫米,平均LCQ得分为11.9,表明QOL降低.
- 患者报告了显著的日常生活障碍,包括语言困难 (58.0%) 和疲劳 (46.6%),女性经历了更大的 QoL 减少和身体/心理影响.
结论:
- 患有RCC/UCC的患者面临着相当大的日常生活负担,包括生活质量受损以及对身体和心理健康的负面影响.
- 慢性咳会影响工作,人际关系和休活动.
- 这项研究表明,女性比男性更容易受到慢性咳的影响.
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