长期接受环环酸盐治疗的高胆血症患者的医疗费用:RECOGNIZE II研究
Abiy Agiro1, Jamie P Dwyer2, Yemisi Oluwatosin3
1US Evidence, US Medical Affairs, AstraZeneca, Wilmington, DE, USA.
ClinicoEconomics and outcomes research : CEOR
|September 27, 2023
概括
用环环酸盐 (SZC) 长期治疗显著降低了患者的高血症相关医疗费用. 这项现实研究发现,与没有SZC治疗相比,SZC治疗为付款人带来了巨大的成本节约.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 药物经济学 药物经济学
- 现实世界的证据.
背景情况:
- 高血症 (血清≥5.1 mmol/L) 与医疗保健支出增加有关.
- 对高胆固醇血症的有效管理策略对于降低相关医疗成本至关重要.
研究的目的:
- 评价长期氧化环酸盐 (SZC) 治疗对高血患者的医疗费用的影响.
- 为了比较SZC治疗和非SZC治疗患者队列之间的与高血相关的和全因医疗成本.
主要方法:
- 使用IQVIA PharMetrics® Plus索赔数据进行了回顾性,比较性研究.
- 包括年龄≥18岁的患有高血的患者和超过6个月的3个月的SZC供应 (2019年7月至2021年12月).
- 在SZC队列和非SZC队列之间进行1:1的倾向评分匹配;主要终点:超过6个月的高血症相关医疗费用.
主要成果:
- 在SZC队列中,平均每患者高血相关的医疗费用减少了49.5% (3798.04美元对7526.51美元;P<0.001).
- 在SZC队列中,所有原因的平均医疗费用下降了21.0% (20,722.23美元对26214.43美元;P<0.01).
- 全因药房费用增长39.8%,但被医疗费用节省所抵消.
结论:
- 长期 (>3个月) 门诊SZC治疗与显著的医疗成本节省有关.
- SZC治疗为患有高血症的患者提供了具有成本效益的管理策略.
- 现实数据支持SZC在高血症管理中的经济效益.
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