结构化的低级重建为无导航器水/脂肪分离的多射击扩散权重的EPI
Yiming Dong1, Kirsten Koolstra2, Ziyu Li3
1C.J. Gorter MRI Center, Department of Radiology, LUMC, Leiden, The Netherlands.
Magnetic resonance in medicine
|September 27, 2023
概括
这项研究引入了一种新的无导航器算法,用于多次射击扩散加权MRI. 该方法有效地纠正运动诱导的相位变化,并分离水/脂肪信号,改善各种解剖学的图像质量.
科学领域:
- 磁共振成像 (MRI) 是一种磁共振成像技术.
- 医学物理 医学物理
- 图像重建 图像的重建
背景情况:
- 多射击回声平面成像 (EPI) 增强了MRI分辨率,但容易受到运动诱导的相位变化.
- 将EPI与化学转移编码 (Dixon) 结合起来,可以分离水/脂肪信号,但会加剧运动工件.
- 现有的方法往往需要导航员或与同时运动校正和水/脂肪分离作斗争.
研究的目的:
- 开发一个无导航器算法,同时进行水/脂肪分离和运动校正,以多次射击扩散权重EPI.
- 为了应对混合EPI-DixonMRI序列中射击到射击相位变化的挑战.
- 为了提高扩散权重MRI的稳定性和适用性.
主要方法:
- 一个代的,基于模型的重建管道,利用结构化的低级规范化.
- 数据驱动的估计和消除射击到射击相位变化.
- 同时分离水和脂肪图像使用化学转移编码.
主要成果:
- 拟议的算法有效地纠正相位变化,并在模拟和体外实验中分离水/脂肪信号.
- 与额外导航和自导航方法相比,证明了卓越的性能.
- 实现了采样不足的数据集的重建,并促进了部分里埃重建.
结论:
- 开发的算法为消除相位变化和分离水/脂肪图像提供了强大的解决方案.
- 它显示了在不同解剖区域推进扩散加权MRI的重大前景.
- 无导航器的方法简化了扫描协议,并提高了临床适用性.
相关概念视频
Mass Spectrometry: Overview
Mass spectrometry is an analytical technique used to determine the molecular mass and molecular formula of a compound. The basic principle of mass spectrometry is to generate ions from the analyte molecule and measure these ion abundances against their molecular mass. One common type of ionization, known as electron ionization or EI, bombards the analyte molecules in the gas phase with high-energy electron beams. The electron beams displace an electron from the molecule and leave behind a...
Mass Spectrometry: Molecular Fragmentation Overview
The ionization of a molecule into a molecular ion inside the mass spectrometer causes instability in the molecule's structure due to the loss of an electron. This eventually leads to the fragmentation or breaking of some bonds in the molecule. The fragmentation occurs predominantly at specific bonds to yield relatively stable fragments.
One type of fragmentation pattern is the cleavage of a single bond in the molecular ion. The cleavage leads to a radical and a cation. The cleavage can occur at...
One type of fragmentation pattern is the cleavage of a single bond in the molecular ion. The cleavage leads to a radical and a cation. The cleavage can occur at...
Chemical Ionization (CI) Mass Spectrometry
The molecular ion peak of a molecule in the mass spectrum provides vital information for molecular identification. However, conventional electron impact ionization can lead to the rapid dissociation of some molecular ions before they reach the detector. A milder ionization method is required to increase the lifetime of such ionized analyte molecules. Chemical ionization (CI) is a gas-phase protonation reaction useful for mass-analyzing analyte molecules that are easily protonated to yield the...
Electrospray Ionization (ESI) Mass Spectrometry
Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
Mass Spectrum: Interpretation
An unknown compound can be established by identifying the molecular ion peak in the mass spectrum. The molecular ion peak is often weak or absent due to the predominance of fragmentation in high-energy electron beams. In such cases, a soft-energy electron beam can be used to scan the spectrum to enhance the intensity of the molecular ion peak. Additionally, chemical ionization, field ionization, and desorption ionization spectra are used to obtain a relatively intense molecular ion peak.To...
Tandem Mass Spectrometry
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...


