用于生物医学应用的抗菌酸涂层是通过微弧氧化制造的
Anna I Kozelskaya1, Ksenia N Verzunova1, Igor O Akimchenko1
1Weinberg Research Center, School of Nuclear Science &Engineering, Tomsk Polytechnic University, 30, Lenin Avenue, 634050 Tomsk, Russia.
Biomimetics (Basel, Switzerland)
|September 27, 2023
概括
含的酸涂层是使用微弧氧化制造的. 用酸和氧化涂层显示出含量最高的和抗菌活性对金黄色葡萄球菌.
科学领域:
- 材料科学 材料科学 材料科学
- 生物材料工程 生物材料工程
- 表面化学 表面化学
背景情况:
- 细菌的抗生素耐药性需要新的抗菌战略.
- 酸涂层对于生物医学应用至关重要.
- 加入抗菌剂可以提高涂层的功能.
研究的目的:
- 为了制造和表征含的酸涂层.
- 为了评估这些涂料的抗菌特性.
- 为了研究电解质成分对结合和释放的影响.
主要方法:
- 微弧氧化被用来制造基于氧化,酸和酸的电解质的涂层.
- 氧化被添加到电解质中,以赋予抗菌性质.
- 分析了涂层形态,结构,化学成分和度.
- 抗菌活性测试针对金黄色葡萄球菌,耐甲基金黄色葡萄球菌和Pseudomonas aeruginosa.
主要成果:
- 尽管添加了均的氧化,但的度在涂层之间有显著的差异.
- 含有酸和氧化的涂层呈现出最高的含量和释放.
- 氧化和氧化涂层显示出对Pseudomonas aeruginosa的优越活性.
- 酸和氧化涂层显示出强大的抗菌作用,对黄金葡萄球菌和耐甲黄金葡萄球菌产生强烈的抗菌作用.
结论:
- 电解质成分极大地影响在酸涂层中的融入和释放.
- 含的涂层为治疗伤口提供有前途的抗菌特性.
- 定制电解质配方允许针对特定病原体具有针对性的抗菌疗效.
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