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相关概念视频

Epigenetic Regulation01:37

Epigenetic Regulation

3.1K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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Gene-Environment Interactions01:20

Gene-Environment Interactions

346
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
346
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

6.6K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.6K
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

6.3K
Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying...
6.3K
Transcription01:10

Transcription

147.1K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
147.1K
Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

46
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
46

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相关实验视频

Updated: Jul 15, 2025

Analyzing Gene Expression from Marine Microbial Communities using Environmental Transcriptomics
13:51

Analyzing Gene Expression from Marine Microbial Communities using Environmental Transcriptomics

Published on: February 18, 2009

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环境表观基因组

Bambarendage P U Perera1, Frédéric Silvestre2

  • 1Department of Environmental Health Sciences, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA.

Epigenomes
|September 27, 2023
PubMed
概括

环境因素影响表观基因组,影响基因表达和生物体的特征. 这些表观遗传变化,特别是DNA甲基化,可以对个体健康和多代进化产生持久的影响.

科学领域:

  • 环境表观遗传学探讨了外部因素如何影响遗传基因功能变化而不改变DNA序列.
  • 专注于诸如DNA甲基化,基因素修饰和非编码RNA等机制.

背景情况:

  • 表观遗传学研究已经扩大到包括环境生物学,调查压力因素如何影响生物体.
  • 表观遗传机制对于理解在不断变化的环境中适应和进化至关重要.
关键词:
通过DNA甲基化.生物标志物 生物标志物乳腺癌 乳腺癌 乳腺癌心脏代谢健康的健康状况生态表观遗传学 生态表观遗传学环境表观遗传学环境表观遗传学人口表观遗传学 人口表观遗传学有毒性 史基因 遗传学毒理学 毒理学 毒理学

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