后COVID-19患者的放射和功能性肺部进化:一项观察性研究
Virgínia Maria Cavallari Strozze Catharin1, Tereza Laís Menegucci Zutin1,2, Elen Landgraf Guiguer1,2,3
1Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, Brazil.
大多数COVID-19后患者在一年内经历肺部改善,胸部成像和肺功能测试显示显著恢复. 然而,一些人可能会在COVID-19感染后出现持续的肺部连续病.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
背景情况:
- COVID-19 (冠状病毒疾病2019) 在全球范围内导致广泛的系统性健康问题.
- 持续的症状和器官损伤是已知的COVID-19后并发症.
研究的目的:
- 评估COVID-19后患者的临床,放射和肺功能恢复.
- 为了确定COVID-19后肺部症状和并发症的流行率.
主要方法:
- 对302名患有COVID-19病史的患者进行了回顾性分析.
- 随着时间的推移,对临床数据,胸部断层扫描 (CT) 和螺旋计结果的评估.
主要成果:
- 常见的COVID-19后症状包括干咳,呼吸不全和胸痛;喘是常见的并发症 (23.5%).
- CT初始平均肺部参与率为69.7%,在6个月内降至37.7%,在6-12个月之间降至20%,在12个月后降至9.9%.
- 在6个月内,CT正常化发生在50.3%,在6-12个月之间发生在23%,在12个月后发生在5.2%,其中17.3%显示残留后续.
- 螺旋测量显示,59.3%在六个月内正常化,12.3%在六到十二个月之间,6.3%在十二个月后,只有3.6%的持续变化.
结论:
- 大多数患者在COVID-19后的一年内表现出显著的放射性和功能性肺复苏.
- 显著的百分比的患者可能会出现残留的肺部继发症,需要持续监测和管理.
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