纳米凝的应用作为有效的药物输送平台,用于皮肤/皮肤外输送
Panoraia I Siafaka1, Ece Özcan Bülbül2, Mehmet Evren Okur3
1Department of Life Sciences, School of Sciences, Faculty of Pharmacy, European University Cyprus, 2404 Nicosia, Cyprus.
Gels (Basel, Switzerland)
|September 27, 2023
概括
纳米凝为通过皮肤传递药物提供了一个有希望的解决方案,克服了局部和透皮应用的自然障碍. 这些纳米载体增强了活性药物成分的传递,改善了溶解性和治疗结果.
科学领域:
- 制药科学 制药科学
- 生物技术是生物技术.
- 材料科学 材料科学 材料科学
背景情况:
- 皮肤作为药物透的重要障碍,对局部和透皮药物输送构成挑战.
- 口服药物给药存在各种缺点,需要使用其他输送途径.
- 有效的皮肤传递,特别是用于伤口愈合,仍然是医学上的一个关键挑战.
研究的目的:
- 审查纳米凝作为载体的应用,以通过皮肤和皮肤传递活性药物成分.
- 讨论纳米凝在制药制造和药物输送系统中的潜力.
主要方法:
- 在药物输送中纳米凝应用的文献综述.
- 对皮肤透和药物溶解性相关的纳米凝特性进行分析.
- 纳米凝作为不溶性药物,基因和疫苗的载体的探索.
主要成果:
- 纳米凝是基于聚合物的纳米网络,具有独特的物理化学特性,包括高表面积和生物相容性.
- 这些纳米载体在提高活性药物成分的可溶性方面显示出潜力.
- 纳米凝对皮肤和皮肤间的施用途径都很有前途,增强了分子的递送.
结论:
- 纳米凝代表了一种可行的方法来克服药物输送的皮肤屏障限制.
- 它们的特性使它们成为各种活性药物成分的有效载体.
- 纳米凝在制药制造中具有重要的未来潜力,用于先进的药物输送系统.
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