捕捉乳腺癌治疗的真实成本:每病例基于活动的分子亚型和特定阶段的成本计算
Anna N Wilkinson1, Jean M Seely2, Moira Rushton3
1Department of Family Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Current oncology (Toronto, Ont.)
|September 27, 2023
概括
乳腺癌治疗费用正在上升,特别是晚期和某些亚型的乳腺癌. 基于活动的成本计算显示,随着疾病的发展阶段,成本显著增加,突出显示需要更新乳腺癌护理的经济模型.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 医疗成本分析 医疗成本分析
背景情况:
- 乳腺癌 (BC) 治疗格局正在随着新的,昂贵的疗法而发展.
- 现有的成本模型不足以捕捉当前的BC治疗费用.
- 需要新的成本计算方法来反映现实世界的BC治疗费用.
研究的目的:
- 根据疾病阶段和分子亚型分层确定乳腺癌治疗的个案成本.
- 应用基于活动的成本计算 (ABC) 方法来准确评估BC成本.
- 为乳腺癌管理提供最新的经济数据.
主要方法:
- 使用基于活动的成本计算 (ABC) 来整合多学科治疗数据.
- 包括诊断,手术,放射,全身疗法和支持性护理的费用.
- 针对不同阶段和乳腺癌分子亚型的每病例计算成本.
主要成果:
- 乳腺癌治疗成本比以前报告的要高,并且因分子亚型而异.
- 随着疾病的发展阶段,成本呈指数级增长,第四阶段的成本高达516,415加元.
- 阶段之间的成本差异可能很大,例如,在IV阶段与DCIS相比,成本差异高达35.6倍.
结论:
- 由于新疗法和生存率增加,乳腺癌治疗费用正在不断上升.
- 该研究为BC治疗提供了实时,基于病例的成本计算.
- 调查结果将有助于评估卫生系统的经济影响,并了解查的成本效益.
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