在瘤术期内草提取物:人类随机对照试验的系统审查和元分析
Elise Cogo1, Mohamed Elsayed1,2,3, Sukriti Bhardwaj1
1Patterson Institute for Integrative Oncology Research, Canadian College of Naturopathic Medicine, Toronto, ON M2K 1E2, Canada.
Current oncology (Toronto, Ont.)
|September 27, 2023
概括
Mistletoe提取物 (ME) 对癌症患者的免疫细胞和生活质量有潜在的益处,但需要更多高质量的研究来确认其在术后期的安全性和有效性.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在癌症治疗中,术后期对于患者的治疗结果至关重要.
- Mistletoe提取物 (ME) 在瘤护理中的潜在作用正在被探索.
研究的目的:
- 为了评估尾提取物 (ME) 在瘤术前期的安全性和有效性.
主要方法:
- 7项随机对照试验 (RCT) 和3项非随机研究的系统审查和元分析.
- 包括的研究评估了ME作为辅助护理或将其与标准癌症治疗进行比较.
主要成果:
- 在ME和没有添加治疗之间,没有发现死亡率或复发率的显著差异.
- 一些研究表明,ME对自然杀手细胞和生活质量有有益影响,特别是在结直肠癌中.
- 在某些情况下,不良事件导致ME停止治疗,但总体而言,没有发现任何重大安全问题. 在所有研究中,偏见的风险是相当大的.
结论:
- 初步数据表明,尾提取物可能对结肠直肠癌患者有鼓励作用.
- 证据受到研究数量,结果变异性和方法论弱点的限制.
- 为了验证这些发现,进一步进行高质量的研究至关重要.
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