相关实验视频
Updated: Jul 15, 2025

06:23
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
4.9K
斯波罗特里克斯巴西利尼斯:流行病学,治疗和最近的发展
Melissa Orzechowski Xavier1,2, Vanice Rodrigues Poester1,2, Mariana Rodrigues Trápaga1,2
1Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), Rio Grande 96200-190, RS, Brazil.
Journal of fungi (Basel, Switzerland)
|September 27, 2023
概括
由Sporothrix brasiliensis引起的运动性三病正在全球范围内蔓延,超越了巴西. 迫切需要新的抗真菌治疗来对抗这种新出现的真菌感染.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 由Sporothrix brasiliensis引起的球菌是一种新出现的菌,引起全球越来越多的关注.
- 有效的治疗对于控制运动三症至关重要,但目前的治疗选择有限.
- 迫切需要新的抗真菌剂,专门针对S. brasiliensis.
研究的目的:
- 系统地审查Sporothrix brasiliensis的全球分布,导致人类和动物的运动三症,特别是在巴西以外.
- 评估对S. brasiliensis.进行测试的现有疗法.
- 突出改善疾病理解,临床教育,医疗保健组织和治疗研究的需要.
主要方法:
- 按照PRISMA指南进行了系统审查.
- 收集了关于S. brasiliensis Sporotrichosis全球分布的数据.
- 通过体外和体内研究评估了各种抗菌剂对S. brasiliensis的抗真菌活性.
主要成果:
- 由 S. brasiliensis 引起的运动性三病已在巴西和三个大陆的其他五个国家报告.
- 阿根廷近年来报告病例显著增加.
- 20种独特的化学物质和8种重新设计的药物在体外表现出活性,其中5种药物在临床前模型中显示出体外有效性.
结论:
- 葡萄 (Sporothrix brasiliensis) 诱导的葡萄病是一种全球性的健康问题,不仅限于巴西.
- 了解疾病流行病学,教育医疗保健专业人员和公众,组织和医疗保健提供是必不可少的.
- 迫切需要进一步研究有效的抗真菌疗法来治疗运动三症.
更多相关视频
相关概念视频
Fungal Phylum Microsporidia
37
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
37
Pulmonary Tuberculosis V
194
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
194
Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
Pulmonary Tuberculosis IV
157
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
157
Pulmonary Tuberculosis I
257
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
257
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K

