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整个膝关节的映射使用一个阶段调节的UTE增血T (PM-UTE-AdiabT) 序列
Yajun Ma1, Michael Carl2, Qingbo Tang1,3
1Department of Radiology, University of California, San Diego, San Diego, California, USA.
Magnetic resonance in medicine
|September 27, 2023
概括
一个新的3D阶段调节的UTE增生T1ρ (PM-UTE-AdiabT1ρ) 序列使整个膝关节关节的映射成为可能. 这种先进的MRI技术为各种膝盖组织提供了准确的T1ρ测量,提高了诊断能力.
科学领域:
- 生物医学工程 生物医学工程
- 磁共振成像是一种磁共振成像技术.
- 肌肉骨成像系统的成像
背景情况:
- T1ρ (在旋转框架中的纵向放松时间) MRI对组织组成敏感.
- 由于组织和运动的复杂性,准确地绘制膝关节关节的T1ρ图是具有挑战性的.
研究的目的:
- 开发和验证一种新型的3D相调节的UTE基T1ρ (PM-UTE-AdiabT1ρ) 序列.
- 为了在临床3T扫描仪上实现全膝关节体积T1ρ映射.
主要方法:
- 该PM-UTE-AdiabT1ρ序列包括磁化重置,亚亚电脉冲,相调节,脂肪和,可变翻转角度和3DUTE圆收购.
- 使用简单的指数拟合进行了T1ρ量化.
- 幻影研究评估了灵敏度,可重复性和与连续波T1ρ.的相关性.
- 该序列应用于ex vivo和in vivo正常的膝盖.
主要成果:
- 幻影研究显示对组合变化的高灵敏度,优异的可重复性和与连续波T1ρ的强烈相关性.
- 在体内获得的T1ρ值为股骨软骨 (77.9 ± 3.9 ms),阴囊 (30.1 ± 2.2 ms),ACL (52.0 ± 3.1 ms),PCL (29.2 ± 2.4 ms),软骨肌 (17.0 ± 1.8 ms) 和肌肉 (57.6 ± 2.8 ms).
结论:
- 开发的3DPM-UTE-AdiabT1ρ序列适合对膝关节的体积T1ρ评估.
- 这种技术可以在临床3T扫描仪上绘制膝盖内的短T2和长T2组织.
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