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Updated: Jul 15, 2025

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
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在儿科患者中对埃斯基塔洛普拉姆和塞特拉林人口的药动力学分析

Ethan A Poweleit1,2,3,4, Zachary L Taylor4, Tomoyuki Mizuno4,5

  • 1Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Clinical pharmacokinetics
|September 27, 2023
PubMed
概括

这项研究分析了埃斯基塔洛普拉姆和塞特拉林在儿童中的药理动力学 (PK). CYP2C19表型显著影响药物暴露,建议对低代谢剂进行剂量调整,以优化焦虑和抑郁症的治疗.

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