在怀孕前和怀孕期间暴露于空气污染对妊娠期糖尿病的影响
Lei Cao1,2, Ruiping Diao3, Xuefeng Shi1
1China Institute for Radiation Protection, Taiyuan 030006, China.
Toxics
|September 27, 2023
概括
空气污染,特别是PM2.5,PM10和NO2,与更高的妊娠糖尿病 (GDM) 风险有关. 发现某些孕妇群体更容易受到这些影响.
科学领域:
- 环境健康 环境健康
- 生殖健康 生殖健康
- 流行病学 流行病学
背景情况:
- 孕期糖尿病 (GDM) 对母亲和婴儿的健康构成重大风险.
- 空气污染对GDM患病率的影响,特别是在城市环境中,需要进一步调查.
- 确定特定的污染物和敏感的暴露时间对于有针对性的干预措施至关重要.
研究的目的:
- 检查中小城市空气污染与GDM之间的关联.
- 为了确定关键的暴露窗口 (预设,怀孕) 和与GDM相关的关键空气污染物.
- 在怀孕妇女的不同人口群体中探索对空气污染的不同易感性.
主要方法:
- 分析了2018年2月至2020年7月期间分娩的9820名妇女的队列.
- 使用了后勤回归和主要组件后勤回归模型.
- 进行了对颗粒物 (PM2.5,PM10) 和二氧化 (NO2) 的暴露评估.
主要成果:
- 在怀孕前和怀孕期间增加对PM2.5和PM10的暴露显著增加了GDM风险.
- 在怀孕期间增加的NO2暴露也与增加的GDM风险有关.
- 30-35岁的孕妇,未婚妇女和受教育程度较低的妇女表现出更高的敏感性.
结论:
- 空气污染,包括PM2.5,PM10和NO2,是GDM的一个重要风险因素.
- 特定的污染物和暴露时间在GDM开发中至关重要.
- 易受伤害的子组需要有针对性的公共卫生战略,以减轻与空气污染相关的GDM风险.
更多相关视频
05:17Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
Published on: April 5, 2024
813
05:31Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
861
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.5K
Pathophysiology of Diabetes
971
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
971
Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Diabetes: Symptoms, Diagnosis, and Complications
573
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
573
Diabetes Mellitus: Overview and Type I Subtype
2.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.7K
Asthma-I: Introduction
2.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.7K
