大麻和其他物质的滥用:影响和监管
Miski Aghnia Khairinisa1, Mohammed Alfaqeeh2, Syauqi Nawwar Rafif1
1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang 45363, Indonesia.
Toxics
|September 27, 2023
概括
尸检分析对于了解控制物质滥用,包括大麻和阿片类药物造成的死亡人数至关重要. 对药物毒性和法规的全面审查有助于减少过量死亡.
科学领域:
- 法医毒理学 法医毒理学
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 控制的药物滥用,包括大麻和非法药物,对公众健康构成重大风险,往往导致严重中毒和死亡.
- 尸检分析对于确定疑似与毒品有关的死亡事故的死亡原因至关重要.
- 了解滥用物质的神经毒性作用和致命剂量对于公共卫生干预至关重要.
研究的目的:
- 提供常见滥用受控物质的全面审查.
- 讨论死后分析方法,致命剂量,毒性机制和监管框架.
- 突出滥用物质对中枢神经系统 (CNS) 的神经毒性影响.
主要方法:
- 关于控制物质滥用的科学文献的叙述性综述.
- 对七个流行药物群体的特征,毒性和监管方面进行分析:大麻,阿片类药物,安非他命类兴奋剂,可卡因,新型精神活性物质和幻觉剂.
- 检查与药物中毒相关的死后分析技术.
主要成果:
- 滥用大麻,阿片类药物,兴奋剂,可卡因,NPS和幻觉剂与增加致命过量风险有关.
- 大多数滥用物质都会产生神经毒性作用,主要针对中枢神经系统.
- 致命剂量水平和特定毒性机制在不同物质类别之间存在显著差异.
结论:
- 对受控物质的严格监管对于减轻危害和减少死亡率至关重要.
- 处方者必须遵守指导方针,以防止转移和滥用处方药.
- 更好地了解药物滥用后果可以为更有效的预防和干预策略提供信息.
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