大麻使用频率和与大麻相关的后果在高风险的年轻人 跨大麻合法化
Amanda Doggett1, Kyla Belisario1, André J McDonald1
1Peter Boris Centre for Addictions Research/Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University/St. Joseph's Healthcare, Hamilton, Ontario, Canada.
JAMA network open
|September 27, 2023
概括
加拿大的娱乐大麻合法化并没有导致大麻使用的增加或高风险年轻人的不良后果. 频繁使用者在合法化后消费量下降,而不频繁使用者显示的变化很小.
科学领域:
- 公共卫生 公共卫生
- 药物使用研究研究 药物使用研究
- 大麻合法化研究 大麻合法化研究
背景情况:
- 娱乐大麻合法化引发了人们对增加使用和不良后果的担忧,特别是在年轻人中.
- 在合法化期间,高风险的年轻成年人对大麻消费模式的纵向数据有限.
研究的目的:
- 调查加拿大娱乐大麻合法化后,大麻使用频率的变化以及高风险年轻人中的相关后果.
- 确定这些变化的潜在调节者.
主要方法:
- 一项纵向观察队列研究从2017年2月至2020年2月跟踪了加拿大安大略省的年轻人.
- 参与者 (n=619) 在入学时年龄为19.5-23.0岁,每4个月进行一次调查.
- 分析了数据以评估大麻使用和后果的变化,根据性别,收入,教育和合法化前使用频率进行调节.
主要成果:
- 在研究期间观察到大麻使用频率和相关后果的总体下降.
- 这些变化被合法化前大麻使用频率显著缓和.
- 常见的合法化前用户在合法化后的使用和后果显著减少.
- 非使用者使用频率略有增加,但后果没有显著变化.
结论:
- 在大麻合法化前经常使用大麻的高风险年轻人在合法化后使用量和后果减少,这表明"衰老"效应.
- 在这个队列中,与大麻使用相关的短期不良结果在合法化期间并没有大幅增加.
- 虽然这项研究没有发现任何显著的不良结果,但不能排除没有合法化的替代轨迹.
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