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Updated: Jul 15, 2025

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Piezo1激活了非正规的EGFR内细胞和信号传导

Carlos Pardo-Pastor1, Jody Rosenblatt1,2

  • 1Randall Centre for Cell & Molecular Biophysics, New Hunt's House, School of Basic & Medical Sciences, Faculty of Life Sciences & Medicine, King's College London, SE1 1UL London, UK.

Science advances
|September 27, 2023
PubMed
概括

机械力通过Piezo1通道激活细胞生长途径,与EGF信号不同. 这种由Piezo1介导的途径涉及Src和p38激酶,驱动细胞循环的重新进入,并可能为再生和癌症提供新的治疗点.

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