在18F-FDG PET/MR上具有甲状腺参与的朗格汉斯细胞囊细胞形成
1From the Department of Radiology, University of Pennsylvania Perelman School of Medicine.
Clinical nuclear medicine
|September 27, 2023
概括
朗格汉斯细胞囊细胞形成 (LCH) 可以模仿儿童的甲状腺癌. 这一案例凸显了活检对于精确诊断部质量的重要性,即使成像显示恶性病.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 儿科瘤学 儿科瘤学
- 核医学是一种核医学.
背景情况:
- 儿童部胀可能是恶性瘤的原因.
- 甲状腺异常需要彻底调查.
- 朗格汉斯细胞囊细胞症是一种罕见的疾病,影响多个器官.
研究的目的:
- 报告一个Langerhans细胞囊细胞形成的病例,在婴儿身上呈现为甲状腺质量.
- 为了说明先进的成像在分期和评估疾病程度方面的作用.
- 为了强调诊断挑战在区分LCH从儿童患者的甲状腺癌.
主要方法:
- 一个18个月大的女孩的病例介绍,她的子胀.
- 诊断工作包括超声波和核心针活检.
- 使用18F-FDG PET/MR和骨调查进行病期和疾病评估.
主要成果:
- 超声波表明扩散扩大,异质甲状腺,最初被认为是甲状腺癌.
- 核针活检证实了涉及甲状腺的朗格汉斯细胞囊细胞形成.
- 18F-FDG PET/MR揭示了一种超代谢性部质量,在没有入侵的情况下包围了重要结构,并排除了骨参与.
结论:
- 兰格汉斯细胞囊细胞瘤应在儿童甲状腺质量的差异诊断中考虑.
- 准确的诊断依赖于组织活检,即使有暗示恶性瘤的成像.
- 综合PET/MR对于对儿科LCH的局部疾病程度进行全面的分期和评估是有价值的.
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