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Updated: Jul 15, 2025

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
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Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules

Published on: October 17, 2014

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一项计算研究,以了解p120-catenin对cadherin cis-dimerization的影响

Zhaoqian Su1, Vinh H Vu2, Deborah E Leckband2,3

  • 1Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

Journal of molecular cell biology
|September 27, 2023
PubMed
概括

内外信号传递,其中p120-catenin (p120ctn) 的细胞内结合会影响细胞表面的阴素功能,至关重要. 这项研究揭示了p120ctn通过改变其细胞外动力学和促进聚类来全质调节阴素的cis-dimerization.

关键词:
通过cadherin介导的细胞粘附.从内到外的信号传输.分子动力学模拟,分子动力学模拟多尺度建模模型的使用.

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