相关实验视频

Updated: Jul 15, 2025

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

在瑞典结核性硬化症中手术的演变:国家注册研究的研究

Kevin Pearsson¹, Erik A Eklund², Olof Rask³

¹Division of Clinical Sciences Helsingborg-Pediatrics, Department of Clinical Sciences Lund, Helsingborg General Hospital, Lund University, Helsingborg, Sweden.

|September 27, 2023

概括

结核硬化综合体 (TSC) 手术后的发作自由度有所改善,随着时间的推移,结核切除术和早期手术的增加. 在TSC患者中,早期的手术干预与更好的结果有关.

科学领域:

神经学神经学
神经外科神经外科
儿科症儿科症

背景情况:

结核性硬化综合体 (TSC) 是一种遗传性疾病,可以导致瘤在包括大脑在内的各种器官中生长.
是TSC的常见症状,通常耐药,需要手术干预.
描述TSC患者的外科结果对于改善治疗策略至关重要.

研究的目的:

分析瑞典一组手术治疗的结核性硬化综合体 (TSC) 患者.
调查手术前调查和手术结果的时间趋势.
在TSC的手术后,确定影响发作自由的因素.

主要方法:

瑞典国家手术登记册的回顾性分析.
两个时期的手术结果的比较:1997-2010年和2011-2018年.
重新评估手术前检查和患者特征.

主要成果:

管切除术后的发作自由度显著增加,从11% (1997-2010) 增加到56% (2011-2018).
早些时候 (1997-2010年) 进行手术的患者出现了更高的发作频率和更多的婴儿.
在晚期观察到更早的手术干预的趋势 (平均年龄为48个月而不是86个月).
前切除术在控制掉落发作方面表现出有效性,成功率各不相同.

结论:

与TSC相关的的手术治疗得到了改善,特别是管切除术,随着时间的推移,自由率有所提高.
早期较高的疾病负担与较差的外科手术结果相关.
前切除术在2010年代初被用于特定的发作类型.

关键词:

卡洛索托米 (Callosotomy) 是一种切除骨头的方法.药物耐药性的治疗方法管切除术 (Tuberectomy) 是一个切除术.结核性硬化综合体结核性硬化综合体

更多相关视频

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Published on: October 2, 2014

$Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note$ 05:54

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

相关概念视频

Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...

Arteries of the Lower Limbs

Arteries of the Lower Limbs

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...