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由PGC1-α驱动的线粒体生物发生有助于在黑色素瘤中形成癌症干细胞表型

Fabrizio Fontana1, Chiara Macchi1, Martina Anselmi1

  • 1Department of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", Università degli Studi di Milano, Milan, Italy.

Biochimica et biophysica acta. Molecular basis of disease
|September 27, 2023
PubMed
概括

黑色素瘤癌干细胞 (CSCs) 依赖于增强的线粒体活动来增长和生存. 准这些线粒体可能提供一种新的治疗策略来阻止黑色素瘤的进展.

关键词:
黑色素瘤是一种黑色素瘤.线粒体生物发生是线粒体生物发生.氧化酸化 (OXPHOS) 是一种这是PGC1-α.癌症干细胞 (CSCs) 是一种癌症干细胞.

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