母亲吸烟对甲状腺功能的影响:常规第一季度超声波异常查结果
Rabia Zehra Bakar1, Caglar Cetin1, Can Yilmaz Yozgat2
1Obstetrics and Gynecology, Bezmialem Vakif University, Istanbul, Turkey.
Zeitschrift fur Geburtshilfe und Neonatologie
|September 27, 2023
概括
这项研究发现,吸烟对甲状腺功能或怀孕早期亚临床甲状腺功能低下没有显著的影响. 孕产妇的甲状腺刺激激素 (TSH) 和自由甲状腺素 (fT4) 水平在吸烟者和非吸烟者之间没有差异.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 怀孕期间吸烟是一个重大的公共卫生问题.
- 孕产妇的甲状腺功能对胎儿发育至关重要.
- 吸烟在怀孕早期对甲状腺激素的影响需要进一步调查.
研究的目的:
- 评估烟草暴露对母亲甲状腺功能的影响.
- 为了确定吸烟和临床下甲状腺功能低下症在孕妇在头三个月期间之间的关系.
主要方法:
- 一项涉及45名孕妇吸烟者和72名非吸烟者的比较研究.
- 使用问卷和测量一氧化碳 (CO) 水平确认吸烟状态.
- 评估母亲的甲状腺刺激激素 (TSH) 和第一季度的自由甲状腺素 (fT4) 水平.
主要成果:
- 在吸烟者 (TSH: 1.48 mIU/L, fT4: 11.43 pmol/L) 和非吸烟者 (TSH: 1.72 mIU/L, fT4: 11.17 pmol/L) 之间没有观察到TSH和FT4水平的统计学显著差异.
- 亚临床甲状腺功能低下的患病率在吸烟者中为8.9%,而非吸烟者中为19.4%,这一差异在统计学上并不显著.
- 吸烟者和非吸烟者之间的身体质量指数 (BMI) 在吸烟者和非吸烟者之间是相似的.
结论:
- 这项研究表明,在怀孕的第一季度,母亲吸烟与甲状腺功能 (TSH,ft4水平) 之间没有统计学上显著的关联.
- 在孕妇吸烟者和非吸烟者之间,观察到的亚临床甲状腺功能低下率没有显著差异.
- 进一步的研究可能是有必要的,以探索潜在的长期影响或未在本初步评估中捕捉到的细微差别.
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