超的高血糖状态 高血糖状态
Spencer S Lovegrove1, Sarah B Dubbs1
1Department of Emergency Medicine, University of Maryland School of Medicine, 110 South Paca Street, 6th Floor Suite 200, Baltimore, MD 21201, USA.
Emergency medicine clinics of North America
|September 27, 2023
概括
超球高血糖状态 (HHS) 是一种严重的糖尿病紧急情况. 关键指标包括高血清度和没有子,需要积极的液体和胰岛素治疗,同时治疗触发性疾病.
科学领域:
- 内分泌学 在内分泌学.
- 内部医学 内部医学
- 紧急医疗 紧急医疗
背景情况:
- 超球高血糖状态 (HHS) 是一种严重的糖尿病紧急情况.
- 医疗卫生和卫生服务局呈现出高发病率和死亡率.
- 在临床实践中,它往往被忽视.
研究的目的:
- 为了区分HHS和糖尿病酸性酸症 (DKA).
- 为了突出HHS的关键诊断特征.
- 概述HHS的推治疗策略.
主要方法:
- HHS和DKA临床特征的比较.
- 确定HHS的特定诊断标记.
- 审查目前的HHS治疗指南.
主要成果:
- HHS的特点是血清度>320mOsm/kg.
- 缺少代谢酸和最小的是关键的差异化特征.
- 常见的触发因素包括感染,中风和急性冠状动脉综合征.
结论:
- 迅速识别和区分DKA对于HHS管理至关重要.
- 积极的体积补充和胰岛素治疗是治疗的主要组成部分.
- 解决潜在的诱发性疾病对于成功的HHS治疗至关重要.
相关概念视频
Hypoglycemia and Glucagon
287
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
287
Glucose Transporters
22.9K
Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
22.9K
Diabetes: Symptoms, Diagnosis, and Complications
573
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
573
SBAR II: Application of SBAR
4.5K
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
4.5K
Pathophysiology of Diabetes
971
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
971
Metabolic States of the Body: The Postabsorptive State
352
The postabsorptive state usually starts about four hours after a meal and lasts until the next meal is eaten. During this time, the digestive system stops absorbing nutrients, and the body uses stored energy reserves to maintain stable blood glucose levels.
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
352


