儿童和青少年的甲状腺手术:来自德国和奥地利多机构数据库的结果
Theresia Weber1, Rainer Hummel1, Christian Vorländer2
1Klinik für Endokrine Chirurgie, Marienhaus Klinikum Mainz, Germany.
The British journal of surgery
|September 27, 2023
概括
这项研究分析了德国和奥地利近期的小儿甲状腺手术结果,发现了常见的良性疾病和晚期甲状腺癌. 虽然生存率很好,但儿童甲状腺癌患者需要更长的随访时间.
科学领域:
- 内分泌学 在内分泌学.
- 儿科手术 儿科手术
- 在瘤学瘤学.
背景情况:
- 儿童甲状腺手术的结果几乎没有记录.
- 关于最近的趋势和并发症的数据有限.
- 多中心研究对于全面分析至关重要.
研究的目的:
- 报告儿童甲状腺手术的最新结果.
- 分析年轻患者的病理和并发症.
- 建立未来研究和临床实践的基准.
主要方法:
- 来自StuDoQT的甲状腺注册表的未来数据收集 (2017年3月 - 2022年8月).
- 包括18岁或更年轻的接受甲状腺手术的患者.
- 对良性和恶性病理,手术并发症和患者人口统计的分析.
主要成果:
- 604名患者 (平均年龄15.4岁,75%为女性) 来自90个机构.
- 常见的良性疾病:结节性喉,卵泡腺瘤,格雷夫斯病.
- 甲状腺恶性瘤包括乳头 (77.8%),毛囊 (10.3%),骨髓 (8.7%) 甲状腺癌,常常与淋巴结转移 (45.9%在PTC).
- 4.9% (早期) 和0.7% (持续) 的病例出现了重复的喉神经损伤.
- 手术后的小甲状腺功能低下与特定的病理和淋巴结解剖相关.
结论:
- 儿科乳头状和卵泡状甲状腺癌经常存在于晚期.
- 乳头甲状腺癌显示持续或复发的淋巴结转移.
- 观察到优异的整体存活率,但延长的随访是必不可少的.
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