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在CTE的残留异常预测克罗恩病的不良结果与内镜愈合

Fangling Zhang¹, Jie Zhou¹, Ling Wang¹

¹Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University. 26th Yuancun the second Road, Guangzhou, Guangdong Province, 510655, China; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, China.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

|September 27, 2023

概括

末透镜愈合的克罗恩病患者的残留CT肠道学异常预测复发. 使用介质水,纤维脂肪增殖和活跃炎症的评分系统可以识别患有不良结果风险较高的患者.

科学领域:

胃肠病学胃肠病学
放射学放射学是一门学科.
炎症性肠道疾病研究研究

背景情况:

在克罗恩氏病 (CD) 患者的计算机断层扫描肠道图 (CTE) 上的残留异常可能表明未来的疾病活动.
了解这些残留发现对于预测预后和指导CD管理中的治疗策略至关重要.

研究的目的:

调查CTE检测到的残留异常在患有EH的CD患者中的预后影响.
开发和验证基于CTE发现的评分系统,以预测不良结果,包括临床复发.

主要方法:

分析了2015年3月至2022年6月期间接受了CTE的140名患有EH的CD患者队列.
在终端大肠和结肠中发现的CTE被评估为特定异常.
考克斯回归分析和卡普兰-梅尔曲线被用来将残留异常与不良结果相关联.

主要成果:

中肠,纤维脂肪增殖和小肠炎症被确定为临床复发的重要危险因素.
结合这三个参数的评分系统表明,得分≥1有效预测临床复发 (HR=4.56).
开发的评分系统显示了各种不良结果的强大预测价值,并得到了验证.

结论:

从残留的CTE异常 (中肠,纤维脂肪增殖,活性炎症) 来得分的评分系统可以准确地预测已经实现内镜治疗的克罗恩病患者的不良结果.
该工具有助于风险分层和个性化治疗策略,用于CD患者在内镜后缓解.

关键词:

计算机断层扫描 (计算机断层扫描) 肠道扫描 (肠道扫描).克罗恩氏病克罗恩氏病是什么?内镜治疗治疗的方法剩余的异常情况.

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