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肺部细胞外基质调节KRT5+基底细胞在肺纤维化中的活性

Richard J Hewitt1,2, Franz Puttur1, David C A Gaboriau3

  • 1National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.

Nature communications
|September 27, 2023
PubMed
概括

异形性肺纤维化 (IPF) 涉及KRT5+基底细胞扩张和肺组织重塑. 细胞外基质 (ECM) 变化,特别是SPARC水平,影响KRT5+细胞迁移和肺中的纤维化过程.

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