吸收,侵袭性CT特征和膜入侵之间的相关性,在腺癌与膜接触的腺癌中
Yingdong Chen1, Qianwen Huang2, Hua Zhong1
1Department of the Radiology, Zhongshan Hospital, Medicine School, Xiamen University, Xiamen, 361004, China.
Scientific reports
|September 27, 2023
概括
特定的CT扫描特征,包括超过10毫米的接触长度和螺纹,可以准确地预测肺癌中膜入侵. 这种组合可以提高肺腺癌的诊断性能.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 肺癌中多接触并不总是表明多入侵 (PI).
- 准确预测PI对于肺癌分期和治疗计划至关重要.
- 计算机断层扫描 (CT) 特性和吸收是PI的潜在成像生物标志物.
研究的目的:
- 为了确定特定的侵入性CT特征或吸收是否可以预测肺腺癌中的肺部侵袭 (PI).
- 为了评估PI预测这些成像特征的诊断效率.
主要方法:
- 对97名切除了固体肺腺癌的患者进行了对比增强的光谱CT扫描的回顾性分析.
- 两个放射科医生对CT特征和吸收的独立评估.
- 后勤回归分析以确定PI预测因素,然后进行准确性分析和ROC曲线以验证.
主要成果:
- 接触长度>10毫米 (OR 4.80,P=0.001) 和螺旋标志 (OR 2.71,P=0.033) 被确定为PI的独立预测因素.
- 摄入量没有显著预测PI.
- 整合接触长度和螺纹增强灵敏度到90%,AUC为0.73.
结论:
- 接触长度>10毫米和螺纹标志的组合显著提高了预测肺腺癌肺部侵袭的诊断性能.
- 这些CT特征为评估PI提供了一种有价值的非侵入性方法,有助于临床决策.
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