对儿童阻塞性睡眠呼吸暂停综合征严重程度的可能危险因素的分析
Lea Dékány1, Viktória Molnár2, András Molnár1
1Department of Otolaryngology and Head and Neck Surgery, Semmelweis University, Budapest, Hungary.
概括
较高的体重指数 (BMI) 百分位数和年龄与儿童阻塞性睡眠呼吸暂停 (OSA) 严重程度的增加有关. 然而,这些因素对预测严重的OSA的临床应用有限.
科学领域:
- 儿科睡眠医学 儿科睡眠医学
- 呼吸系统健康 呼吸系统健康
- 肥胖与健康 肥胖与健康
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是儿童常见的呼吸系统疾病.
- 影响OSA严重性的因素需要进一步调查,以有效管理.
研究的目的:
- 评估身体质量指数 (BMI) 百分位数,喘,性别和年龄对儿科阻塞性睡眠呼吸暂停 (OSA) 严重性的影响.
- 评估儿童严重OSA的BMI百分位数和年龄的预测值.
主要方法:
- 追溯分析921名儿童 (2-18岁) 通过多睡眠学诊断出OSA.
- 统计分析包括ANCOVA,斯皮尔曼相关性和接收器操作特征 (ROC) 曲线.
主要成果:
- 更高的BMI百分位与增加的OSA严重程度 (p<0.001) 有显著的关联.
- 年龄也与OSA严重程度有显著的关系 (p=0.01).
- 无论是喘还是性别都没有显示出与OSA严重程度的显著关联.
结论:
- 体重指数百分位数和年龄是儿童OSA严重程度的重要决定因素.
- 虽然具有预测性,但BMI百分位数和年龄对于识别严重的OSA具有有限的临床实用性.
- 肥胖是OSA的关键风险因素,特别是在年幼的儿童中,老年,超重和肥胖的儿童面临更高的严重OSA风险.
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