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Updated: Jul 15, 2025

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胺合成酶CERS4基因下调与结直肠癌中的KRAS突变有关

Tamuro Hayama1,2, Kotaro Hama3,4, Tsuyoshi Ozawa5

  • 1Department of Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. tamuro@med.teikyo-u.ac.jp.

Scientific reports
|September 27, 2023
PubMed
概括

脂代谢,特别是胺合成酶4 (CERS4) 的表达,与结直肠癌 (CRC) 的进展有关. 在CRC患者中,较低的CERS4水平与KRAS突变和增加的血管入侵相关.

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