一个异质图卷积注意力网络方法用于对自闭症谱系障碍进行分类
Lizhen Shao1,2, Cong Fu3,4, Xunying Chen3,4
1Beijing Engineering Research Center of Industrial Spectrum Imaging, School of Automation and Electrical Engineering, Beijing, 100083, China. lshao@ustb.edu.cn.
BMC bioinformatics
|September 27, 2023
概括
这项研究引入了一种新的深度学习模型,用于使用脑成像数据对自闭症谱系障碍 (ASD) 的分类. 不同质图卷积注意网络 (HCAN) 有效地利用受试者表型信息,在ASD诊断中实现高准确性.
科学领域:
- 神经科学是一个神经科学.
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 自闭症谱系障碍 (ASD) 是一种复杂的神经发育状况.
- 功能性磁共振成像 (fMRI) 和深度学习对ASD分类有希望.
- 现有的图形神经网络难以完全整合受试者表型数据.
研究的目的:
- 开发一种新的深度学习模型,以改进ASD分类.
- 为了提高诊断准确性,利用fMRI和表型数据.
- 解决当前方法中同质图形结构的局限性.
主要方法:
- 提出了一个异质图形卷积注意力网络 (HCAN) 模型.
- 构建了一个整合fMRI和表型数据的异质人口图.
- 采用多层HCAN进行特征提取,然后使用MLP分类器.
主要成果:
- 在ABIDE I数据集 (871名受试者) 上获得了82.9%的分类准确性.
- 与同一个数据集的现有方法相比,表现出优异的性能.
- 通过使用fMRI数据验证了模型在分类ASD中的有效性.
结论:
- 该HCAN模型有效地整合了异质图形卷积网络和注意力机制.
- 对象表型特征得到充分利用,提高了分类性能.
- 拟议的方法显示了使用fMRI诊断大脑功能障碍的巨大潜力.
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