气球辅助肠镜能预测小肠克罗恩病患者的疾病结果吗?
Ji Eun Na1,2, Sung Noh Hong3, Ji Eun Kim1
1Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
气球辅助肠镜 (BAE) 有效评估小肠克罗恩病 (CD) 活动. 在BAE上,较高的疾病得分和狭窄预测CD患者的手术风险增加.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 炎症性肠道疾病是什么
背景情况:
- 有限的研究存在于气球辅助肠镜 (BAE) 评估小肠克罗恩病 (CD) 活动.
- 对于CD患者的长期结果,BAE的预测价值仍未得到充分研究.
研究的目的:
- 评估BAE在评估内镜疾病活动中的实用性.
- 确定BAE发现是否预测小肠CD的长期手术风险.
主要方法:
- 对111名小肠癌患者的回顾性分析.
- 通过BAE通过小肠简单内镜评分对克罗恩病 (SES-CD) 评估的疾病活性.
- 考克斯的比例危险模型用于分析基于SES-CD和内镜发现 (,狭窄) 的手术风险.
主要成果:
- 小肠SES-CD得分≥7显著增加了手术风险 (HR 6.31,p=0.013).
- 在BAE期间"无法传递"的狭窄也显著增加了手术风险 (HR 12.34,p=0.014).
- 任何的存在都没有显示出与手术风险的显著关联.
结论:
- BAE对于评估小肠CD的疾病活性有价值.
- BAE的发现,特别是高的SES-CD得分和严重的狭窄,预测了未来的外科手术需求.
- 建议为临床实践进一步研究和优化BAE.
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