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Updated: Jul 15, 2025

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使用GONAD进行细胞类型特异性和系统的发育转录因子在体内的分析

Christoph Wiegreffe1, Simon Ehricke1, Luisa Schmid1

  • 1Medical Faculty, Institute of Molecular and Cellular Anatomy, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.

Biology
|September 28, 2023
PubMed
概括

研究人员在小鼠中通过卵管核酸输送 (i-GONAD) 方法开发了一种改进的基因组编辑. 这种技术有效地修改了像Bcl11a和Bcl11b这样的转录因子 (TF),以研究它们在细胞发育中的作用.

关键词:
在 Bcl11a 中,在 Bcl11bb 中.这是一个FLBIO标签.这就是i-GONAD.转录因子是一种转录因子.

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