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Updated: Jul 15, 2025

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在抑制类固醇生成的化合物中探索硫分子的潜力

Tomasz M Wróbel1,2, Katyayani Sharma3,4,5, Iole Mannella6

  • 1Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Medical University of Lublin, Chodźki 4a, 20093 Lublin, Poland.

Biomolecules
|September 28, 2023
PubMed
概括

研究人员开发了新型化合物,可以抑制细胞染色体P450 17α-基酶/12,20-酶 (CYP17A1). 这些化合物表现出双重抑制的潜力,向CYP17A1和阿尔多基因还原酶1C3 (AKR1C3) 两者.

关键词:
在 AKR1C3C3 中.在CYP17A1中.酶抑制抑制酶的抑制.前列腺癌是前列腺癌.

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