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Updated: Jul 15, 2025

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初级免疫缺陷基因的罕见变异及其在严重COVID-19中的功能伙伴

Maryam B Khadzhieva1,2,3, Dmitry S Kolobkov2, Darya A Kashatnikova2

  • 1The Laboratory of Clinical Pathophysiology of Critical Conditions, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 107031 Moscow, Russia.

Biomolecules
|September 28, 2023
PubMed
概括

严重的COVID-19遗传可能涉及原发性免疫缺陷疾病 (PID) 基因作为核心元素. 它们的功能性伴侣 (FPs) 充当了外围基因,其中罕见的变体有助于年轻成年人的疾病严重程度.

关键词:
核心和外围基因的基因.PID基因的功能合作伙伴 (FPs).全源性模型是什么?一次性免疫缺陷 (PID) 基因蛋白质与蛋白质相互作用 (PPI)罕见的高影响力 (HI) 变种.发生严重的COVID-19整体外因子测序的测序

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