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深髓静脉和MRI标记与脑出血亚型有关

Dan Wang^1,2, Yayun Xiang¹, Yuling Peng¹

¹Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, 1# Youyi Road, Yuan Jiagang, Chongqing 400010, China.

|September 28, 2023

概括

深髓静脉 (DMV) 评分和MRI标记器有效地区分脑内出血 (ICH) 亚型在脑小血管疾病 (CSVD) 患者. DMV分数也与CSVD严重程度和成像标志物相关联.

科学领域:

神经学神经学
放射学放射学是一门学科.
血管医学血管医学

背景情况:

大脑小血管疾病 (CSVD) 是大脑内出血 (ICH) 的常见原因.
区分ICH亚型对于了解疾病机制和预后至关重要.
深髓静脉 (DMV) 和MRI标记是CSVD和ICH的潜在指标.

研究的目的:

评估深髓静脉 (DMV) 评分和磁共振成像 (MRI) 标记器在脑内小血管疾病 (CSVD) 患者中区分不同脑内出血 (ICH) 亚型的性能.

主要方法:

对232名心血管内脏病患者的临床和成像数据的回顾性分析.
将患者分为与高血压动脉病变 (HTNA) 相关的ICH,与大脑粉样血管病变 (CAA) 相关的ICH和混合ICH组.
评估半球中DMV得分与ICH相反,并分析各种MRI标志物.

主要成果:

在HTNA相关和混合ICH组之间,DMV得分显著不同 (p < 0.01).
在ICH亚型中,MRI标志物和CSVD负担得分各不相同 (p < 0.05).
与混合ICH相比,与HTNA相关的ICH显示出更高的深白质强度 (DWMH) 和周血管空间 (PVS);与CAA相关的ICH与年龄增加有关 (p < 0.001).
DMV分数与大脑微型血流 (CMB),PVS,DWMH,周周结膜白质超强度 (PWMH) 和CSVD负担相关,但没有缺口. 年龄是DMV得分严重性的独立风险因素 (p < 0.001).

结论:

DMV分数,CSVD标记和CSVD负担分数与不同的ICH亚型有关.
DMV分数反映了CSVD的严重程度,并与特定的CSVD成像标记物相关联.

关键词:

磁力共振成像 (MRI) 标记器大脑小血管疾病是大脑小血管疾病.深层髓静脉深层髓静脉脑内出血脑内出血

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