在动物细胞膜的新模型中,类水果的胡卜素和 Askorbic 酸之间的抗氧化相互作用
Marcelo P Barros1,2, Jaime Zacarías-Garcia1, Florencia Rey1
1Food Biotechnology Department, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Catedrático Agustín Escardino 7, Paterna, 46980 Valencia, Spain.
Antioxidants (Basel, Switzerland)
|September 28, 2023
概括
类水果的胡卜素和酸 (ASC) 对抗自由基. 纳多科特普通提取物显示出最好的整体抗氧化活性,特别是在生物模拟细胞膜模型中.
科学领域:
- 食品科学 食品科学 食品科学
- 营养生物化学 营养生物化学
- 抗氧化剂研究 抗氧化剂研究
背景情况:
- 类水果与慢性退行性疾病的减少有关,这归因于诸如胡卜素和 Askorbic 酸 (ASC) 等抗氧化剂.
- 了解类成分的特定抗氧化机制和相互作用对于健康益处至关重要.
研究的目的:
- 研究类胡卜素提取物的基清除和单一氧气灭能力.
- 在各种系统中评估这些活动,包括生物模拟动物细胞膜模型 (AML).
- 评估阿斯科布酸 (ASC) 与类胡卜素的协同作用.
主要方法:
- 液体色谱被用来描述四种类品种的胡卜素组成.
- 在有机溶剂,水溶液,小和AML系统中进行了扫除和灭试验.
- 添加了10微米度的甲酸 (ASC),以评估其对抗氧化活性的影响.
- 使用C11-BODIPY光试验来测量针对AML氧化物的清除活性.
主要成果:
- 随着系统的不同,胡卜素灭活性有显著的变化;在有机溶剂中",Ruby Valencia" (富含利科) 卓越,而"Nadorcott"普通 (富含β-密素) 在微粒中优越.
- 亚酸 (ASC) 显著增强了所有类提取物在细胞系统中的灭活性.
- "纳多科特"普通提取物表现出对AML氧化最强的清除活性 (-70%),其次是"瓦伦西亚"和"Pinalate"子.
- 所有测试的类提取物都表现出平衡的抗氧化特性,其中"纳多科特"普通的整体活性略高.
结论:
- 类胡卜素和酸 (ASC) 具有强大的抗氧化特性,其活性取决于生物环境.
- 生物模拟脂质体系统 (AML) 有效地模拟细胞抗氧化剂相互作用.
- 富含β-加密素的"纳多科特",由于其平衡和强大的抗氧化剂特性,具有显著的健康益处.
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