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Updated: Jul 15, 2025

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

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揭示与寡合性Aβ诱导的Src激活相关的早期事件

Sandra I Mota1,2,3, Lígia Fão1,2, Patrícia Coelho1,2

  • 1CNC-UC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

Antioxidants (Basel, Switzerland)
|September 28, 2023
PubMed
概括

阿尔茨海默氏病 (AD) 涉及可溶性粉样β oligomers (AβO) 激活Src. kinase. 这项研究揭示了AβO触发Src激活,导致升,线粒体功能障碍和神经元中的氧化应激,这表明Src是治疗标.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.这种NMDA受体是NMDA受体.Src 铁氨酸激酶的作用线粒体功能障碍 线粒体功能障碍线粒体形态的形态学

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