一个多方面的干预及其对挪威养老院抗生素使用的影响
Nicolay Jonassen Harbin1,2, Jon Birger Haug3, Morten Lindbæk1,2
1Antibiotic Center for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, 0450 Oslo, Norway.
Antibiotics (Basel, Switzerland)
|September 28, 2023
概括
养老院的质量改善干预措施使总抗生素使用量减少了15.8%. 对尿路感染的口服抗生素使用显著减少,这表明有针对性的策略是有效的.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗生素耐药性是一个日益严重的全球健康问题.
- 养老院是抗生素过度使用和感染的高风险环境.
- 质量改善干预措施可以减轻医疗保健机构对抗生素的滥用.
研究的目的:
- 评估多方面质量改善干预措施对挪威养老院抗生素使用的影响.
- 评估整体抗生素消费和尿路感染 (UTI-AB) 特定抗生素使用的变化.
主要方法:
- 在33个养老院实施了一项为期12个月的干预,包括会议,教育课程,反报告和临床检查清单.
- 药房销售数据 (DDD/100 BD) 测量了全身抗生素使用.
- 线性混合模型分析了与对照县相比,抗生素使用的基线变化.
主要成果:
- 干预组的总抗生素使用量下降了15.8% (8.68至7.31 DDD/100 BD),但与对照县没有显著差异.
- 治疗尿路感染的口服抗生素使用 (UTI-AB) 减少了32.8% (4.08至2.74 DDD/100 BD),比对照人群的减少要大得多.
- 该干预措施显示UTI-AB的显著减少,但整体抗生素使用减少需要进一步改进战略.
结论:
- 多方面的干预可以有效地减少特定抗生素的处方,如尿路感染,在养老院.
- 干预策略可能需要进一步调整,以实现整体抗生素使用的显著减少.
- 有针对性的质量改善举措显示出优化长期护理机构抗生素管理的前景.
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