加拿大消费者可购买的和鱼的扩展频谱β-乳糖酶产生肠道细菌-使用编典框架的风险概况
F Carl Uhland1, Xian-Zhi Li2, Michael R Mulvey3
1Centre for Foodborne, Environmental and Zoonotic Infectious Diseases, Public Health Agency of Canada, Guelph, ON N1H 7M7, Canada.
Antibiotics (Basel, Switzerland)
|September 28, 2023
概括
在加拿大零售鱼和中检测到产生扩展谱β-乳糖酶 (ESBL) 的肠道细菌 (ESBL-EB),这是世卫组织优先病原体组. 建议进一步监测,以评估这些抗生素耐药细菌在海鲜中的潜在风险.
科学领域:
- 食品安全 食品安全
- 抗微生物耐药性 抗微生物耐药性
- 水生微生物学 水生微生物学
背景情况:
- 扩展谱β-乳糖酶 (ESBL) 产生的肠道细菌 (ESBL-EB) 是世卫组织确定的人类关键病原体.
- 这些细菌对第三代头素 (3GC) 具有抗性,在全球水产养殖和水生环境中存在.
研究的目的:
- 评估加拿大零售和鱼,关键的水产养殖物种ESBL-EB的当前知识.
- 评估这些海鲜产品中与ESBL-EB相关的潜在风险.
主要方法:
- 根据"食品法典关于食品传播抗菌素耐药性风险分析指南" (Codex Guidelines for Risk Analysis of Foodborne Antimicrobial Resistance) 制定了一个风险概况.
- 关于ESBL-EB在水生环境,宿主物种和生产水平中的存在的文献审查和数据分析.
主要成果:
- 肠杆菌和ESBL-EB已经在各种水生环境,宿主物种和生产阶段被确定.
- 在加拿大零售商提供的进口海鲜中检测到ESBL-EB.
结论:
- 虽然无法确定鱼和对人类健康的最终风险,但ESBL-EB在零售海鲜中的存在得到证实.
- 需要加强对海鲜中的ESBL-EB的监测,使用鱼和作为最初的目标.
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