来自中国东部的烧伤住院患者的伤口感染的危险因素和病原体
Siqi Zhou1, Shuzhen Xiao1,2, Xuedong Wang1,2
1Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Antibiotics (Basel, Switzerland)
|September 28, 2023
概括
烧伤感染 (BWI) 影响60%的患者,烧伤深度,区域和延迟住院是关键风险因素. 通过抽样培养的早期监测有助于有效管理BWI.
科学领域:
- 传染性疾病 传染性疾病
- 烧伤护理 烧伤护理
- 微生物学 微生物学
背景情况:
- 烧伤感染 (BWI) 是烧伤患者发病和死亡的主要原因.
- 了解BWI的发病率,导致因素和细菌进展对于有效的患者管理至关重要.
研究的目的:
- 分析烧伤感染的发病率,危险因素和细菌进展.
- 确定与烧伤患者BWI发展相关的独立风险因素.
主要方法:
- 来自580名被烧伤患者的临床数据的回顾性分析,这些患者被录入第三级医院.
- 使用单变量和多变量逻辑回归,以及卡普兰-梅尔生存分析.
- 评估细菌分离物和抗生素耐药性模式,以追踪微生物进化.
主要成果:
- 60%的患者 (348/580) 患有BWI,其中47%发生在燃烧后的第一个星期.
- 炎的独立风险因素包括烧伤深度,烧伤面积和延迟初次住院治疗.
- 金黄色葡萄球菌是最常见的病原体;观察到从格拉姆阳性细菌转变为格拉姆阴性细菌的过渡时间更短. 更长的住院时间是保护性的.
结论:
- 准确评估影响BWI的因素对于及时和适当的临床管理至关重要.
- 常规的拭子培养可以作为监测烧伤患者微生物状态的宝贵工具.
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