在长期经历COVID-19后症状的个体中,呼吸道肌肉训练计划后,EQ-5D-5L指数和VAS的最小临床重要差异
Tamara Del Corral1,2, Raúl Fabero-Garrido1, Gustavo Plaza-Manzano1,2
1Department of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain.
Biomedicines
|September 28, 2023
概括
对于EuroQol-5D问卷 (EQ-5D-5L) 索引和视觉模拟量表 (VAS) 的最小临床重要差异,确定了长期COVID-19后症状. EQ-5D-5L VAS有效地区分了改善,当其临床重要差异的最小值被超过时.
科学领域:
- 康复医学是康复的医学.
- 临床结果评估评估临床结果评估
- 后COVID-19的后续影响
背景情况:
- 长期的COVID-19后症状会影响生活质量.
- 需要标准化的结果测量来评估治疗疗效.
- 通常使用的是EuroQol-5D问卷 (EQ-5D-5L) 索引和视觉模拟尺度 (VAS).
研究的目的:
- 在长期出现COVID-19后症状的个体中,确定EQ-5D-5L指数和VAS的最小临床重要差异 (MCID).
- 确定哪项措施更好地区分临床改善.
- 根据MCID分类对结果的变化进行比较.
主要方法:
- 一个随机对照试验的二次分析.
- 涉及42名长期出现COVID-19后症状的人.
- 进行了为期8周的呼吸肌训练计划.
主要成果:
- 对于EQ-5D-5L指数,MCID确定为0.262,对于VAS指数则为7.5.
- EQ-5D-5L VAS在改善组和未改善组之间显示了可接受的歧视 (AUC=0.78).
- 超过VAS MCID与肌肉功能和运动耐受性显著改善相关.
结论:
- EQ-5D-5L VAS是评估长期COVID-19后症状治疗有效性的一个有价值的工具.
- 汽车安全系统显示了可接受的区分能力,特别是当MCID被超越时.
- 身体功能的改善与超过VAS MCID有关.
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