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Updated: Jul 22, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

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由Leishmania donovani引起的皮肤莱什曼病的诊断工具:叙述性审查

Sachee Bhanu Piyasiri1, Rajika Dewasurendra1, Nilakshi Samaranayake1

  • 1Department of Parasitology, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 0800, Sri Lanka.

Diagnostics (Basel, Switzerland)
|September 28, 2023
PubMed
概括

由Leishmania donovani引起的皮肤雷什曼病 (CL) 存在诊断挑战,特别是在斯里兰卡等地区. 本综述评估了与L. donovani相关的CL的各种诊断方法,以帮助控制工作.

关键词:
莱什曼尼亚的捐赠人皮肤上的莱什曼病.诊断的准确性 诊断的准确性直接的聚合方式.组织病理学 组织病理学免疫学诊断 免疫学诊断 免疫学诊断显微镜 显微镜是指使用显微镜.分子诊断 分子诊断 分子诊断皮肤病变 皮肤病变

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A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line12:22

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

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In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice

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Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...