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Updated: Jul 15, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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光学基因组映射:整合结构变异以获得精确的同源重组缺陷得分计算计算

Nikhil Shri Sahajpal1, Ashis K Mondal2, Ashutosh Vashisht2

  • 1Greenwood Genetic Center, Greenwood, SC 29646, USA.

Genes
|September 28, 2023
PubMed
概括

与目前的方法相比,光学基因组映射 (OGM) 在检测同源重组缺陷 (HRD) 信号方面具有更高的灵敏度. 这种先进的技术可以改善针对性治疗的患者分层,如PARP抑制剂和药物.

关键词:
人力资源发展人员得分同类重组缺陷的同类重组缺陷通过光学基因组映射进行基因组映射.

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