全基因组关联研究揭示了棕大米中黄素总含量的遗传基础

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Haijian Xia¹, Xiaoying Pu², Xiaoyang Zhu¹

¹Beijing Key Laboratory of Crop Genetic Improvement, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.

|September 28, 2023

概括

研究人员确定了控制米粒中黄胺含量的关键基因. 这一发现有助于培育富含黄酸的品种,用于疾病预防和治疗.

科学领域:

植物遗传学植物遗传学
营养科学营养科学
农业科学农业科学

背景情况:

黄类药物具有抗炎,抗氧化和抗癌性质.
富含黄的米品种在预防癌症和心脑血管疾病等慢性疾病方面具有潜力.
现有的研究主要侧重于大米叶和幼苗中的黄胺调节,在了解谷物特异性含量方面存在差距.

研究的目的:

为了研究大米粒中全黄素含量 (TFC) 的遗传基础.
在棕大米中识别高TFC的水生殖质.
为了精确地确定候选基因,负责在米粒中的黄类积累.

主要方法:

全基因组关联研究 (GWAS) 用于633个加入的米核心集合.
使用压缩混合线性模型检测定量特征位置 (QTL).
候选基因通过链接不平衡 (LD) 分析,SNP位置,基因表达和单种类型分析来确定.

主要成果:

鉴定出了十种优秀的米生殖质,其TFC超过300毫克/100克.
在棕中检测到了53个与TFC相关的QTL.
从两个主要的QTLs (qTFC1-6和qTFC9-7) 确定了8个候选基因,包括LOC_Os01g59440和LOC_Os09g24260.

结论:

这项研究阐明了棕大米中TFC的遗传基础.
已识别的候选基因为繁殖计划中的标记器辅助选择提供了目标.
繁殖富含黄酸的米品种可以促进疾病预防,并作为癌症和心脑血管疾病的辅助治疗.

关键词:

在 QTL 时段,你会得到 QTL.这种类型的黄类药物是flavonoid.功能性大米是一种功能性大米.基因基因基因基因胚胎细胞的资源是胚胎细胞.

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