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甲状腺癌中的CTC,ctDNA和外体:一篇综述

Wenwen Wang¹, Zhiyao Zheng^1,2, Jianyong Lei¹

¹Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

International journal of molecular sciences

|September 28, 2023

概括

液体活检,分析循环瘤DNA (ctDNA),循环瘤细胞 (CTC) 和外体,显示了改善甲状腺癌诊断,治疗监测和预后的前景. 这种方法为有效管理甲状腺癌提供了一种新的方法.

科学领域:

在瘤学瘤学.
分子诊断学分子诊断
生物标志物发现发现

背景情况:

全球甲状腺癌发病率正在上升,这在诊断,治疗和预后方面带来了挑战.
目前对甲状腺癌的诊断和预后方法有局限性.
液体活检为克服这些挑战提供了一种最少的侵入性方法.

研究的目的:

审查甲状腺癌中液体活检的临床潜力.
探索循环瘤DNA (ctDNA),循环瘤细胞 (CTC) 和外体在甲状腺癌管理中的作用.
为未来的甲状腺癌液体活检研究提供参考.

主要方法:

对甲状腺癌中液体活检组件 (ctDNA,CTC,外体) 的现有文献的综述.
从液体活检中分析诊断和预后生物标志物.
评估液体活检在预测治疗反应中的作用.

主要成果:

液体活检组件显示出作为甲状腺癌的诊断和预后生物标志物的潜力.
液体活检可以帮助监测治疗反应.
液体活检技术的进步为甲状腺癌研究提供了新的途径.

结论:

液体活检在甲状腺癌的早期检测,监测和预后方面具有重大前景.
进一步的研究和液体活检的临床应用是有必要的,以改善甲状腺癌患者的治疗结果.

关键词:

在CTC中,使用CTC.ctDNActDNA是什么意思外基因组是外基因组中的一个.液体活检活检液体活检甲状腺癌甲状腺癌甲状腺癌

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