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从原始羊奶中分离出来的导致乳腺炎的葡萄球菌和益生菌乳酸细菌的基因组和表型特征
Ilias Apostolakos1, Theodora Skarlatoudi1, Kornilia Vatavali1
1Department of Dairy Research, Institution of Technology of Agricultural Products, Hellenic Agricultural Organization "DIMITRA", 3rd Ethnikis Antistaseos St., 45221 Ioannina, Greece.
International journal of molecular sciences
|September 28, 2023
概括
在原始羊奶中细菌的分子表征表明,虽然葡萄球菌具有毒素和抗生素耐药性基因,但乳酸细菌 (LAB) 是安全的,具有作为有益的食品添加剂的潜力.
科学领域:
- 食品微生物学 食品微生物学
- 基因组学就是基因组学.
- 细菌遗传学 细菌遗传学
背景情况:
- 乳制品对于营养至关重要,但可能含有影响安全的微生物.
- 乳酸细菌 (LAB) 和葡萄球菌在生牛奶中很常见,对健康和食品质量有不同的影响.
研究的目的:
- 进行LAB和来自原始绵羊奶的葡萄球菌的综合分子和表型表征.
- 评估这些细菌群体在乳制品应用中的安全性和功能潜力.
主要方法:
- 整个基因组测序的测序
- 表型特征表征的表型特征.
- 生物信息学分析
- 鉴定毒性和耐药性基因的鉴定.
主要成果:
- 葡萄球菌表现出毒素和粘附基因,其中一些分离物属于与医院感染相关的序列类型. 在葡萄球菌中检测到多个抗生素耐药性基因.
- 乳酸细菌 (LAB) 没有固有的毒性基因,但具有细菌素和碳水化合物活性酶基因,表明安全性和潜在益处.
- 在两个细菌群体中都发现了移动遗传元素,这表明了基因转移的潜力.
结论:
- 乳酸细菌 (LAB) 适合作为食品添加剂使用,因为它们缺乏毒性和具有有益特征.
- 来自原始羊奶的葡萄球菌可能会由于毒性和抗生素耐药性基因而带来风险.
- 了解细菌遗传学对于提高牛奶和乳制品的安全性和质量至关重要.
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