假牙治疗对唾液代谢物的影响:试点研究
Narumi Ichigaya1, Norishige Kawanishi1, Takuya Adachi1
1Department of Fixed Prosthodontics, Kanagawa Dental University, Yokosuka 238-8580, Japan.
International journal of molecular sciences
|September 28, 2023
概括
牙膏治疗通过增加唾液体积和改变唾液代谢物来改善口腔舒适度. 这项研究显示,在接受新假牙的患者中,唾液组成的变化,以及增强的功能.
科学领域:
- 口腔健康 口腔健康
- 生物化学 生物化学
- 老年学是一门学科.
背景情况:
- 在使用假牙的老年人中,口腔不适和口腔干燥很普遍.
- 唾液体积与这些症状有关,但在假牙使用后唾液成分的变化尚不清楚.
研究的目的:
- 研究假牙治疗对唾液代谢物概况的影响.
- 分析与改善口腔功能相关的唾液组成的变化.
主要方法:
- 唾液流出 (休息和刺激) 和效率在21名牙治疗前后的患者中被测量.
- 进行了唾液代谢组分析,以识别和量化代谢物.
主要成果:
- 牙膏处理显著提高了效率和唾液分泌量.
- 代谢组分析检测到61种唾液代谢物,在静止 (4种代谢物) 和刺激 (21种代谢物) 唾液中观察到显著的度变化.
- 在两种唾液类型中,四种关键代谢物在治疗后的度显著降低.
结论:
- 牙膏的使用不仅通过增加唾液体积,而且通过改变唾液代谢物成分来增强的功能.
- 这些发现表明口腔假肢,唾液生物化学和口腔舒适性之间存在复杂的相互作用.
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