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用RNA-Seq与两个新的RPTEC细胞系对重复脏损伤的洞察

B Alex Merrick1, Negin P Martin2, Ashley M Brooks3

  • 1Mechanistic Toxicology Branch, Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

International journal of molecular sciences
|September 28, 2023
PubMed
概括

开发了两种永生脏近接管道上皮细胞系,以模拟损伤. 西斯普拉丁诱导了协调的损伤和修复反应,而阿弗拉托克辛B1在一个细胞系中表现出特定的毒性.

关键词:
在RNA-seqqq.非洲毒素B1是什么?西斯普拉丁 (cisplatin) 是一种制剂.永生化就是永生化.脏 脏 脏 脏人类的新生是nephrogenesis.毒性 毒性 毒性脏近端管道 脏近端管道翻译学 翻译学 翻译学 翻译学

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...