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嘴唇和裂儿童的口腔微生物群:一个系统性审查
Jacek Świtała1, Magdalena Sycińska-Dziarnowska1, Gianrico Spagnuolo2,3
1Department of Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, Poland.
Journal of clinical medicine
|September 28, 2023
概括
患有唇裂和/或裂 (CLP) 的儿童的口腔微生物群显示出不一致的发现. 需要更多的研究来了解口腔微生物群对CLP口腔健康管理的影响.
科学领域:
- 微生物学 微生物学
- 儿科牙科 儿科牙科
- 遗传学 是一个遗传学.
背景情况:
- 唇裂和/或裂 (CLP) 是一种先天性疾病,影响口腔结构和功能.
- 皮细胞形会改变口腔微生物群的组成.
- 了解这些变化对于管理受影响儿童口腔健康至关重要.
研究的目的:
- 系统地审查和巩固有关儿童的口腔微生物群的现有证据.
- 为了确定CLP患者口腔微生物群研究中的模式和差异.
- 突出未来在CLP口腔健康领域进行调查的领域.
主要方法:
- 在主要的科学数据库 (PubMed,科学网,Scopus,Embase) 中进行全面的文献搜索.
- 纳入标准侧重于评估儿科CLP群体口腔微生物群的研究.
- 使用纽卡斯尔-太华尺度 (NOS) 进行包含研究的质量评估.
主要成果:
- 从最初的422篇文章中,包括了12项研究,显示出显著的异质性.
- 与对照人群相比,CLP患者的*Streptococcus mutans*和*Lactobacillus*水平的结果是不同的.
- 一项研究表明,在患有CLP的儿童中, *Candida* 种植殖的流行率更高.
结论:
- 目前关于CLP口腔微生物群的科学证据是不确定的和异质的.
- 进一步的高质量研究对于明确了解CLP的口腔微生物群至关重要.
- 这些发现强调了为患有CLP的个体制定量身定制的口腔健康战略的必要性.
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